PharmGED: Pharmacogenetic Effect Database
Identifieur interne : 001457 ( Main/Exploration ); précédent : 001456; suivant : 001458PharmGED: Pharmacogenetic Effect Database
Auteurs : C. J. Zheng ; L. Y. Han ; B. Xie ; C. Y. Liew ; S. Ong ; J. Cui ; H. L. Zhang ; Z. Q. Tang ; S. H. Gan ; L. Jiang ; Y. Z. Chen [Singapour]Source :
- Nucleic Acids Research [ 0305-1048 ] ; 2006-12-06.
Abstract
Prediction and elucidation of pharmacogenetic effects is important for facilitating the development of personalized medicines. Knowledge of polymorphism-induced and other types of drug-response variations is needed for facilitating such studies. Although databases of pharmacogenetic knowledge, polymorphism and toxicogenomic information have appeared, some of the relevant data are provided in separate web-pages and in terms of relatively long descriptions quoted from literatures. To facilitate easy and quick assessment of the relevant information, it is helpful to develop databases that provide all of the information related to a pharmacogenetic effect in the same web-page and in brief descriptions. We developed a database, Pharmacogenetic Effect Database (PharmGED), for providing sequence, function, polymorphism, affected drugs and pharmacogenetic effects. PharmGED can be accessed at free of charge for academic use. It currently contains 1825 entries covering 108 disease conditions, 266 distinct proteins, 693 polymorphisms, 414 drugs/ligands cited from 856 references.
Url:
DOI: 10.1093/nar/gkl853
Affiliations:
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Chen</name><affiliation></affiliation><affiliation></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Singapour</country></affiliation></author></analytic><monogr></monogr><series><title level="j">Nucleic Acids Research</title><idno type="ISSN">0305-1048</idno><idno type="eISSN">1362-4962</idno><imprint><publisher>Oxford University Press</publisher><date type="published" when="2006-12-06">2006-12-06</date><biblScope unit="volume">35</biblScope><biblScope unit="supplement">suppl_1</biblScope><biblScope unit="page" from="D794">D794</biblScope><biblScope unit="page" to="D799">D799</biblScope></imprint><idno type="ISSN">0305-1048</idno></series><idno type="istex">54A6EEFE7F097388A63ED627D9CFC24B49461130</idno><idno type="DOI">10.1093/nar/gkl853</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0305-1048</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">Prediction and elucidation of pharmacogenetic effects is important for facilitating the development of personalized medicines. Knowledge of polymorphism-induced and other types of drug-response variations is needed for facilitating such studies. Although databases of pharmacogenetic knowledge, polymorphism and toxicogenomic information have appeared, some of the relevant data are provided in separate web-pages and in terms of relatively long descriptions quoted from literatures. To facilitate easy and quick assessment of the relevant information, it is helpful to develop databases that provide all of the information related to a pharmacogenetic effect in the same web-page and in brief descriptions. We developed a database, Pharmacogenetic Effect Database (PharmGED), for providing sequence, function, polymorphism, affected drugs and pharmacogenetic effects. PharmGED can be accessed at free of charge for academic use. It currently contains 1825 entries covering 108 disease conditions, 266 distinct proteins, 693 polymorphisms, 414 drugs/ligands cited from 856 references.</div></front></TEI><affiliations><list><country><li>Singapour</li></country></list><tree><noCountry><name sortKey="Cui, J" sort="Cui, J" uniqKey="Cui J" first="J." last="Cui">J. Cui</name><name sortKey="Gan, S H" sort="Gan, S H" uniqKey="Gan S" first="S. H." last="Gan">S. H. Gan</name><name sortKey="Han, L Y" sort="Han, L Y" uniqKey="Han L" first="L. Y." last="Han">L. Y. Han</name><name sortKey="Jiang, L" sort="Jiang, L" uniqKey="Jiang L" first="L." last="Jiang">L. Jiang</name><name sortKey="Liew, C Y" sort="Liew, C Y" uniqKey="Liew C" first="C. Y." last="Liew">C. Y. Liew</name><name sortKey="Ong, S" sort="Ong, S" uniqKey="Ong S" first="S." last="Ong">S. Ong</name><name sortKey="Tang, Z Q" sort="Tang, Z Q" uniqKey="Tang Z" first="Z. Q." last="Tang">Z. Q. Tang</name><name sortKey="Xie, B" sort="Xie, B" uniqKey="Xie B" first="B." last="Xie">B. Xie</name><name sortKey="Zhang, H L" sort="Zhang, H L" uniqKey="Zhang H" first="H. L." last="Zhang">H. L. Zhang</name><name sortKey="Zheng, C J" sort="Zheng, C J" uniqKey="Zheng C" first="C. J." last="Zheng">C. J. Zheng</name></noCountry><country name="Singapour"><noRegion><name sortKey="Chen, Y Z" sort="Chen, Y Z" uniqKey="Chen Y" first="Y. Z." last="Chen">Y. Z. Chen</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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